You have to give credit to a movie like Rampage for featuring a scene in which its lead character—in this case played by Dwayne Johnson—gazes upon one of its C.G.I. creations and says “you’re big shit.” That line invites a lot of easy expansions. Rampage is, it turns out, just about a bunch of big shit. And it is itself a big pile of, well, you get it. So coming right out and speaking its core truth aloud like that is reckless, but maybe respectable. I wish only that the rest of director Brad Peyton’s film had that same half-conscious moxie. An entire movie of that could be a lot of fun.
The bulk of Rampage is, alas, a slog, as passionless as I’d imagine the fandom is for the I.P. the film is based on. Some of us remember Rampage, a 1986 arcade game about generic King Kong and Godzilla types knocking down buildings, but do any of us love it? Rampage the movie doesn’t really seem to care either way, relying some on half-assed nostalgia (there’s a Rampage arcade console glimpsed in the background of the villain’s office, about as lazily direct a nod as could be) but mostly hoping that audiences will thrill to the movie’s wan energy because it’s a Dwayne Johnson vehicle, and he’s basically the biggest movie star there is right now.
Which is true. Johnson ended 2017 and began 2018 with Jumanji: Welcome to the Jungle, an action comedy that has made nearly a billion dollars worldwide and is the latest in a nearly unbroken (Baywatch, whoops) string of hits. He’s a big, bankable name. And yet as Rampage proves, his charisma can only take him—and a movie—so far. Rampage dumps Johnson into a blank role and figures that’s enough to make things work. “It’s The Rock, doin’ stuff!” Yeah, sure, it is The Rock doing stuff. But it’s stuff we’ve seen him do before, in better movies. Rampage probably needed more of a built-in joke to put Johnson to good use, some device or wink that gestured toward the obviousness of his casting. That never arrives, and so we get a Johnson performance that’s about as bored as we are watching the movie.
Johnson plays Davis Okoye, a former special ops Army guy turned primatologist who’s tasked with saving the world—or at least Chicago—when a mysterious substance from a top-secret space-station laboratory crashes to Earth and makes oversized monsters out of a Wyoming wolf, a Florida gator, and a beloved albino gorilla named George, who is also Davis's best friend. Rampage starts off as a kind of workplace comedy, with Davis training two young scientists (Breanne Hill and Jack Quaid) who seemed destined to hook up by the end of the movie, and palling around with a dorky sidekick played by P.J. Byrne. We figure that when the ape gets big, all that stuff will travel along on the adventure.
But, nah. Once the monster mash gets going, Rampage forgets about all that and becomes a mostly serious action story, assiduously avoiding a lot of its camp potential. The film hurries toward a city-destroying climax that arrives about one set piece too early, before pausing to gravely take in the destruction wrought and lives lost, and then closing things out with an ape making the S-E-X hand motion familiar to most third-graders. (You can make it with emojis. That one.) I in no way wanted the movie to be longer, but it probably should have been—maybe with another action sequence or something the movie could have stumbled upon some idea of itself.
And it could have done more with 2017 Oscar nominee Naomie Harris, who plays the regretful scientist who cooked up this wicked serum. She and Johnson aren’t really given much opportunity to build a rapport, and Harris—one of the more reliably engaging actresses working on-screen—goes to waste.
As for the monsters? They’re fine. George is a motion-capture creation who, while credible, cannot match the stunning detail of his cooler, older cousins from the Planet of the Apes films. (It’s weird to arrive at a point where I’ve grown tired of slow-motion shots of apes flying through the air, arms in attack position.) The wolf and the alligator are more cartoonish, and I didn’t really care about them, as nuisances or villains or just cool things to look at.
I wish, too, that the film spent more time with its archvillain, Claire, a steely corporate don played by Malin Akerman (wigged and willing, if not entirely able). Same for Jake Lacy, who plays Claire’s whinging brother. Theirs is a weird, unexpected dynamic to find in a movie like this, and it bears further teasing out. Perhaps that will happen when this is remade or rebooted in 30 years, the people of the future clamoring for it as much as we were clamoring for this one.
Rampage spent a reported $120 million to get this all done, and I guess I see it—in a should-be-more-dizzying plane-crash scene, in the toppling of the Willis (née Sears) Tower, in the monsters’ articulated movements. But none of it has any ingenuity or weight or purpose behind it. Another rude little trick George the gorilla does is occasionally flip his pal Davis the middle finger. I wish Rampage had that same puckishness, that it would say nyah nyah as it gave us the bird. At least that would be a mood. But the movie would need a large dose of space gas for that to happen. Without it, Rampage doesn’t even have the energy to be a little aggressive.
(CNN) Dwayne Johnson seemingly stars in a movie about every four months, which in the last fiscal year has included "Jumanji" (good) and "Baywatch" (not so much). Enter "Rampage," another game-inspired action vehicle, which falls somewhere between his recent hit and last summer's sun-soaked flop.
Mostly, this effects-heavy film from director Brad Peyton (who previously directed Johnson in "San Andreas" and "Journey 2: The Mysterious Island") has the unpretentious feel of a 1950s monster movie, with a rogue science project unleashing a trio of genetically edited beasts bent on destruction. It's not much of a leap, frankly, from nuclear perils of the past -- the overgrown ants in "Them" or "Tarantula."
As usual, it falls to a couple of mismatched scientists to try saving the day, paired with the one government official who isn't a complete moron. Helpfully, one of those scientists happens to have a special-forces background, allowing him to spend much of the movie doing all kinds of The Rock-like things.
That, of course, would be Johnson's Davis Okuye, a primatologist whose prize subject -- a sign-language-fluent albino gorilla named George -- unluckily runs afoul of a pathogen that plummets from the sky, courtesy of an avaricious corporation. It's headed by a cartoonish pair of villainous siblings, providing a veritable buffet of scenery-chewing for Malin Akerman.
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Davis is pretty quickly thrown together with Dr. Kate Caldwell (Naomie Harris, deserving more after her turn in "Moonlight"), a scientist turned whistleblower, who worked for the bad guys and thinks she might know a cure. In the meantime, George begins to grow dramatically and become more aggressive, as do two other creatures that encountered the glowing goop.
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Rampage is a real head-scratcher: Either it’s the dumbest movie I’ve seen in a while, or it’s secretly a work of genius.
Or, I guess, why not both?
“Based” on an arcade game from the 1980s that was later ported over to home video game systems, Rampage stars Dwayne “The Rock” Johnson as a primatologist at the San Diego Wildlife Sanctuary who finds himself trying to save the world when his best buddy, an ape named George, gets infected by a fast-moving gene modification that turns him into an enormous, rage-filled, deadly killing machine.
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It’s both a blindingly predictable pastiche of an action movie — absolutely nothing happens here that you haven’t seen in a movie before, with the possible exception of some crass sign-language humor from a giant gorilla — and weirdly charming. To the extent Rampage succeeds, it does so specifically because it knows it doesn’t have a single original thought in its head, and it’s not even going to try to convince you otherwise. It’s a movie about smashing things, and things getting smashed, and also it has The Rock.
If that sounds like an appealing thing to watch at the end of a long day, then this is the movie for you. Go knock yourself out. You’ll have fun — and it’s possible you might leave the theater with something to think about too.
Rampage puts a twist on the arcade game, but not on the action movie formula
In the Rampage game, players picked one of three monsters and tried to reduce various cities to rubble, over and over again, while eluding military onslaught. In the movie, our heroes are trying to keep that from happening.
This twist results in a movie with a synopsis that reads like something most people would cook up if they were asked to sketch out a generic action movie plot in 20 minutes. In the prelude, a research spacecraft transporting some kind of huge, fierce creature blows up, but not before a scientist on board escapes in a pod with the “samples.” Then her pod blows up, and the samples survive and land on Earth — one in Wyoming, where a wolf finds it, one in the Everglades, where an alligator locates it, and one in the San Diego Wildlife Sanctuary, where good-natured George stumbles across it.
The research has to do with genetic modification, and it is, of course, both kind of illegal and being conducted by a Big Bad Corporation headed by a sibling pair: dim-but-pretty Brett Wyden (Jake Lacy) and his considerably more cutthroat sister Claire (Malin Akerman), who have a big office at the top of a building where they stalk about making evil plans and peering at screens, as befits a pair of villains.
Meanwhile, Davis Okoye (Johnson), the primatologist who raised George from birth, finds that his friendly, funny gorilla friend has been subsumed by a raging monster. The movie centers on his quest to keep George safe, which leads to him teaming up with a scientist named Dr. Kate Caldwell (Naomie Harris), who used to work for the Wydens, and eventually a sardonic government operative named Harvey Russell (Jeffrey Dean Morgan), who delivers quips with a drawl. As a radio frequency emitted by the Wydens draws the rapidly growing, destructive creatures to Chicago, the trio follows in hot pursuit, and the military starts closing in as well.
And so, yes, this movie has it all: greedy corporate villain, smart scientist, strong and sensitive hero, big monsters, impending destruction, and a very modest message, not pushed too hard, suggesting that it’s humans who are the real animals.
That’s not exactly a strike against it. Action movies like this are meant to be explosive and loud and cathartic, and maybe a little funny. Sure, Rampage has some plot holes, but it definitely doesn’t care, and you really don’t need to either. This is a movie based on an arcade game; the goal is to get to the big fight.
It’s also shot in a clear and coherent way; you pretty much always know where you’re located spatially during the long climactic action sequence, which is more than can be said for, say, the Transformers movies, or even a great many Marvel movies. It’s oddly comforting to watch huge fight sequences that feel this straightforward — rather than trying to make you dizzy, they just want to make you cheer.
Dwayne Johnson headlines Rampage, but the script doesn’t seem to realize it
Most importantly, Rampage has Dwayne Johnson, one of the few remaining movie stars who can open a movie just because he’s in it. (His last movie, Jumanji: Welcome to the Jungle, has made so much money that it recently became the highest-grossing Sony release of all time.) The best parts of Rampage are his scenes with George, which are genuinely funny; the gorilla has an excellent sense of humor. But — is this weird to say? oh well — the pair’s chemistry is also great, and the movie’s only truly touching moments result from their relationship.
But while Johnson is the movie’s greatest strength, he’s also, curiously, its weakest link. Someone appears to have made a miscalculation when writing Johnson’s character. People are constantly accusing Davis of being a bit of a misanthrope — of preferring the company of animals over people, of “not liking” people. That’s his defining characteristic as a person: He doesn’t like people.
Except Johnson absolutely cannot telegraph a dislike of people. He’s affable and polite, with a winning smile, and we never see him be anything other than kindly toward human or animal unless they deserve it. Certainly he prefers the company of animals — I mean, he is a primatologist — and sure, his best friend is a gorilla, but it’s impossible to see him as antisocial or unfriendly. If you have Johnson in your action movie, you rewrite the screenplay around him. Davis would have been much more convincing as “shy” than “curmudgeonly,” but even that would have been a stretch given Johnson’s megawatt charisma.
But that’s a minor quibble. Rampage wants to be a smash-’em-up action movie, and it does that just fine. And if you (like I) want to overthink it, there’s a possibility that it might actually be brilliant.
Okay, but what if Rampage is actually incredibly smart?
The movie’s setup is that DNA from a variety of creatures is being spliced into one package that can be delivered to a single animal, which then takes on some of the others’ characteristics. (So a wolf, for instance, might not just become enraged once infected, but also develop the capabilities of both a porcupine and a flying squirrel.) And, importantly, it also becomes extremely large, and just keeps growing larger and larger.
In a weird way, this works as a metaphor for the film itself. Rampage was a fun arcade and video game with a simple conceit (SMASH THINGS) and not much more. But infected with cinematic DNA, it becomes this weird hybrid monster, taking on characteristics that feel lifted from any number of other action movies ranging from King Kong to Pacific Rim.
And besides being just a lot of movie, it’s one that’s filled with destruction. The most unnerving part of watching Rampage is that you’re not sure how you’re supposed to feel about all this destruction. By the end, presumably millions of people have died and whole sections of cities and buildings have been flattened. The destruction is unthinkable.
But it ends on a cheery upbeat note anyhow — you wouldn’t want to dwell on the chaos and destruction too long because it might just kill the mood — which is both completely predictable for a movie like Rampage and, well, kind of disturbing. Seeing people die in digital projection is not exactly like seeing an 8-bit city get flattened.
And yet the movie’s only social critique, if it has one, is the suggestion that the cruel genetic modification of animals will lead to chaos and death of humans. While Rampage is almost certainly not some kind of stealth critique of big, loud movies full of senseless violence, it almost works on that level anyway, the movie’s plot as a metaphor for the movie’s genre.
As I say: There’s almost no way that’s what Rampage is up to. It is, by all appearances, not a movie with highfalutin aspirations, and that’s why it’s pretty fun. But it’s hard not to wonder, just a little, if Rampage is secretly much smarter than it pretends to be.
Rampage opens in theaters on April 12.
W
e here at STAT cover CRISPR a lot. But it’s not every day we get to cover Dwayne “The Rock” Johnson.
The Rock and the genome-editing technology meet in a new movie, “Rampage,” coming out Friday. Through a freak accident, a gorilla, a wolf, and a crocodile ingest some CRISPR complexes. The animals — whose genomes become edited to make them stronger, bigger, faster, and more aggressive — soon wreak havoc on the city of Chicago.
It’s packed with action, gratuitous destruction, and an anti-poaching message, along with at least a dozen references to CRISPR, some of which are even accurate, say STAT reporters (and amateur movie critics) Megan Thielking and Andrew Joseph, who saw an advanced screening this week. Here are their thoughts — both scientific and cinematic — on the film. This conversation contains spoilers.
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MEGAN: So that was incredible.
ANDREW: This movie has everything: rich biotech baddies with clothes as fancy as their skyscraper headquarters; meditations on how mankind is just as primitive as the animal kingdom (and how we’re actually a horrible and much worse species); and a gigantic wolf with a taste for helicopters. But before we dive into the movie, let’s give a bit of background. Megan, in addition to being a serious science journalist, you’re a big Dwayne “The Rock” Johnson fan. How did we end up at this advanced screening?
MEGAN: I have been working up a STAT pitch on this movie for months. This movie features both science (my beat) and The Rock looking contemplatively out over a cornfield (my aesthetic). My original idea was to review the movie with an expert in genome-editing. I actually invited four CRISPR experts, all of whom were “busy.” Dejected, I then invited Drew.
ANDREW: Fifth choice, I’ll take it.
MEGAN: So the movie opens with a title screen that reads: “In 1993, a breakthrough new technology, known as CRISPR, gave scientists a path to treat incurable diseases through genetic editing. In 2016, due to its potential for misuse, the U.S. Intelligence Community designated genetic editing a ‘Weapon of Mass Destruction and Proliferation.’”
It was a huge relief to see CRISPR mentioned right from the get-go, because I really sold this story to our editors. It also made me feel better about expensing Sour Patch Kids and Raisinets.
ANDREW: To get technical for a second, the title screen is sort of accurate. Yes, James Clapper, then the director of national intelligence, did list genome-editing as a threat in 2016. But when I saw the 1993 line, I kind of chuckled to myself. At first, I thought, sorry, Jennifer Doudna and Feng Zhang, apparently The Rock beat you by like 20 years, your patent claims are worthless. But then I thought more about it and realized what they were referring to. This history of modern CRISPR discovery does, by some accounts, date back to 1993, even though the term CRISPR wasn’t used for another decade or so. And the title page suggests that scientists were using the system to edit genomes 25 years ago, which we know was not the case — that’s a much more recent feat. Anyway, I’ll get off my soapbox now.
Megan, to my surprise, the movie started in space. What’s up with that?
MEGAN: I was not surprised whatsoever that this movie started in space. But, essentially, an evil company is testing CRISPR in space on a lab rat. Only the rat becomes a gigantic rat, the space shuttle explodes, and three CRISPR vials fall to earth. Enter Dwayne Johnson and his best friend, George, the albino gorilla he rescued from poachers and who he communicates with using sign language.
George and two other animals — a wolf and a crocodile — are “infected” with CRISPR. It makes them grow to gigantic proportions and become very aggressive. And in the wolf’s case, it also grew bat wings. But that’s not exactly how CRISPR works.
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ANDREW: I knew this movie was going to be good when one of the astronauts who is trying to escape the shuttle is frantically radioing back to earth. Someone over the radio chimes in that “the test subject is a rat,” and the astronaut replies, “Not anymore.”
And, yes, that’s not exactly how CRISPR works, but it’s not completely off base either! The idea is that the biotech company “weaponized” CRISPR research and introduced the genes of a bunch of other animals into our three monster-animals to give them traits such as those bat wings, or the spikes of some other animal, or the strength or regenerative abilities of certain kinds of bugs. This is all explained very quickly in some exposition by our disgraced yet heroic geneticist played by Naomie Harris (whom I last saw in “Moonlight,” and here’s hoping that, like that movie, “Rampage” scores a surprise best picture win at the Oscars). “I’m talking about extremely specific results,” says Naomie, who, in my mind, I am on a first-name basis with.
One question I have is whether these animal features are polygenic as opposed to tied to one gene. That would make it a lot harder to introduce them into another species. But scientists have CRISPR’d beagles to make them super jacked, so it’s not insane that CRISPR could be used to change the features of an animal. Whether it could be used to double the size of a gorilla overnight, well, that might be a different story. And for the beagles, the CRISPR’ing happened when the dogs were embryos, not fully grown.
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The CRISPR’d animals of “Rampage” also become super aggressive, and behavior might be harder to change through editing. Maybe they just ramped up testosterone production somehow? I don’t know, Naomie didn’t explain that part.
You raised a good point as we left the movie, Megan. Where are the regulators?
MEGAN: All of the CRISPR work in this movie seemed to be WILDLY unregulated. There’s no FDA cameo here. There’s no Scott Gottlieb in skinny jeans. There is Jeffrey Dean Morgan, whom I will refer to as Denny Duquette, his character in “Grey’s Anatomy,” from this point forward. He plays a government agent with a faint Foghorn Leghorn accent who helps The Rock and Naomie Harris take on the CRISPR company, called Energyne.
ANDREW: Best line from Jeffrey Dean Morgan (said in his weird Foghorn Leghorn accent, which is not faint at all): “When science s***s the bed, I’m the guy they call to clean the sheets.”
MEGAN: It’s Denny Duquette, but, yes, that was amazing. In real life, there’s a whole system that keeps research in the U.S. involving CRISPR in check. The Food and Drug Administration and the National Institutes of Health regulate CRISPR as it relates to medical research, of course. But the Environmental Protection Agency and the Department of Agriculture also play a role in overseeing uses of CRISPR. And the Department of Defense — which is interested in genome-editing as a potential bioterrorism threat — has poured a lot of money into CRISPR research. So there are a lot of people overseeing this kind of work. Not just Denny.
ANDREW: Exactly, although the dastardly siblings running Energyne (who complain about their stock price tanking after their space shuttle explodes!) maybe found a way around all of them, you know, by like doing their work in space. Anyone home at NASA?
On a different note, this did make me think of a common movie plot point. As our colleague Damian Garde wrote last year, Hollywood loves a biopharma villain. There’s clearly some fear among the public about what scientists can do, particularly when it comes to rewriting the code of life. I do wonder if this movie will be people’s introduction to CRISPR. Are they going to go home and Google it and see headlines invoking “designer babies”? Is this just going to make people scared of CRISPR, even if they know that it probably won’t lead to a mutant crocodile that can King-Kong-style crawl up the Sears Tower? This is totally made up, but I imagine the marketing people at CRISPR Therapeutics are discussing this right now!
MEGAN: Side note, the director of this movie 100 percent took a Chicago architecture boat tour, because they hit all the major landmarks. But, yes, I do think this will be the first introduction a lot of people have to CRISPR. And as much as I absolutely loved this movie — I will be seeing it at least four more times in theaters, thanks MoviePass — I do think it played fast and loose with some of the science around CRISPR, which is a real thing that actually exists. I know it’s science fiction, but the closest thing I could find on the crew list to a science adviser was a “genetics lab tech advisor.”
ANDREW: I’m definitely giving this movie too much credit, and you’re absolutely right, but there were things in the movie that made me think of real CRISPR issues. Naomie Harris’ character was trying to use CRISPR to cure her brother of some unidentified disease. And her big discovery was how to ensure that CRISPR complexes could be delivered to every cell in the body, not just a few. Granted, efficient CRISPR delivery had some not-great consequences when it happened to a crocodile, but it’s a huge goal for researchers using CRISPR or other types of gene therapy for clinical purposes: ensuring that edits happen in enough cells to, for example, generate enough of a normal protein to overcome the faulty protein produced by a certain disease mutation.
MEGAN: At least The Rock and the rest of the “Rampage” team own up to the fact that they take “great liberties with the science” in the film’s production notes. Here’s what The Rock said: “The science is fascinating. But we had to maintain that balance between delivering on a scientific perspective that makes sense and making sure we’re right around the next corner winking at the audience and letting them know we’re all in on this: Hey, we’re making a big, fun movie about a crocodile with 1118 giant teeth, and a gorilla the size of a house, who likes to flip me off.”
As an audience member, I will gladly let The Rock wink at me, even if it means sparing a little scientific accuracy.
ANDREW: I did hear you giggling a lot whenever The Rock was on screen.
MEGAN: Who wasn’t?
Let’s talk about how they want to stop the destruction of the entire city of Chicago and potentially the world by delivering an antidote. The antidote, we’re told, will curb the unchecked aggression of the animals but not reverse the other changes, like bringing George back to his original 7-foot-tall size. But that’s more in line with Pokemon than actual CRISPR science. In theory, you could re-edit the genes of an animal again after editing them initially with CRISPR, but there’s no magic solution to immediately reverse CRISPR and bring peace to the Windy City like the movie suggests. And if there were, I’m not confident you could deliver it by putting it in the purse of a woman who then gets consumed by a CRISPR’d animal. Which happens.
ANDREW: The antidote at one point is described as a giant “chill pill.”
And here I am again making a reach, but, whatever, this movie’s got layers. When they were talking about an antidote or reversing those changes, I immediately thought about gene drive! Granted, that’s a different use of CRISPR — editing animals to force traits throughout a whole species — and reversing gene drive isn’t just re-editing the animals that have already been edited. But researchers who are working on gene drive are cognizant of the fact that playing with nature can have unintended consequences, so it’s probably a good idea to have a real-life CTRL-Z at the ready.
STAT special movie correspondents Megan Thielking and Andrew Joseph pose with George and Dwayne Johnson at the AMC Loews in Boston. Kid at movie theater for STAT
MEGAN: Agree wholeheartedly. I and the entire city of Chicago and the suburbs (Go Cats!) would like to thank science for the antidote. Final thoughts on the science, Drew?
ANDREW: I’m sorry I’m still harping on this, but back to the fear of genome-editing. Obviously, there are a whole lot of ethical and safety issues involved with playing with DNA, and I think most scientists take those seriously. But it’s interesting to see this movie given that we now have treatments on the market involving editing DNA. Sure, they’re not CRISPR-based therapies, but clinical trials using CRISPR are recruiting patients. And the CAR-T therapies and the gene therapy Luxturna (see this piece by our colleague Eric Boodman to get a sense of how it works) are big deals for patients, and there are a lot more coming down the pike.
MEGAN: That was as subtle a product placement as the Dave & Buster’s sign that gets torn off a building in “Rampage.”
ANDREW: I did see you scramble to write that part down in your notebook when it happened. Anyway, your final thoughts, Megan, the Statler to my Waldorf?
MEGAN: There was one health-related subplot here we didn’t get to, which was how The Rock was able to take on three giant animals, scale burning buildings, and save the world after being SHOT THROUGH THE ABDOMEN with roughly half an hour left in the movie. He said the bullet missed all of his vital organs, but still. Swoon. In my notes, I scribbled, “The Rock. Man of many talents. Also gorilla whisperer.”
One final question: If you were in a real-life “Rampage” situation, what would you do?
ANDREW: The first lesson is, listen to Dwayne “The Rock” Johnson. If he says don’t put George the gorilla on a plane, don’t put him on a plane! How about you?
MEGAN: I would hop on The Rock’s back and let him carry me while I used my inhaler.
ANDREW: So what do you think, can we convince our editors to send us to an advanced screening of The Rock’s next movie? See you at “Skyscraper”?
MEGAN: Catch me at the midnight premiere.
Megan’s grades:
Scientific: A for effort, B- for execution
Cinematic: Two out of two Rock biceps
Andrew’s grades:
Scientific: B-, though honestly I haven’t stopped thinking about it
Cinematic: Let’s just say I can’t wait for “Rampage 2: Editin’ Boogaloo”
Thanks to STAT’s very own CRISPR expert, Sharon Begley, for reviewing this review to make sure we didn’t screw anything up.
